CAS 917389-32-3|LeterMovir
Cov roj formula: C29H28F4N4O4
Molecular Luj: 572.55
EINECS:
Purity: 97% Min.
Pob: 1 g / 5 g / 25 g / 100 g / 1 kg
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Khoom Taw qhia
Taw qhia
Letermovir (AIC246, MK-8228) yog ib qho tshiab los tiv thaiv CMV compound uas tsom rau cov kab mob kis kab mob enzyme complex thiab tseem ua haujlwm tawm tsam cov kab mob uas tiv taus DNA polymerase inhibitors.
Specification ntawm CAS 917389-32-3|LeterMovir
Yam khoom | SPECIFICATION |
Boiling point | 7 06,5d |
pka ua | 4.00 |
cia temp. | Muab kaw rau hauv qhuav, Khaws rau hauv lub tub yees, hauv qab -20 degree |
ceev | 1.37 g / cm3 |
Synthesis ntawmCAS 917389-32-3|LeterMovir
Cov xwm txheej:
Theem #1: (S)-methyl 2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-({ {8}}(3-methoxyphenyl)piperazin{10}}yl)-3,4-dihydroquinazolin-4-yl)acetate (2S,3S)-2 , 3-bis((4-methylbenzoyl)oxy)succinate ethyl acetate Nrog disodium hydrogenphosphate; tert-butyl methyl ether Hauv dej rau 2h;
Theem #2: Nrog sodium hydroxide Hauv dej ntawm 60 degree; rau 5h;. Inert cua;
Siv:
Humphrey, Guy R.; Dalby, Stephen M.; Andreani, Teresa; Xiang, Bangping; Luzung, Michael R.; Nkauj, Zhiguo Jake; Shevlin, Michael; Christensen, Melodie; Belyk, Kevin M.; Tso, David M.
[Organic Process Research and Development, 2016, vol. 20, nr 6, p. 1097 - 1103]
Cim npe nrov: cas 917389-32-3,917389-32-3,letermovir, nqe, hais, luv nqi, hauv Tshuag, muag
