CAS: 148504-34-1|Calcein-AM

Lub npe: Calcein-AM

Synonyms: N, N′-[[3′,6′-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-2′ ,7′-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1′-Bis[(acetyloxy)methyl] Ester; Calcein Acetoxymethyl Ester; TIAB SA 689290

CAS: 148504-34-1

Purity: 95 feem pua

Molecular Formula: C₄₆H₄₆N₂O₂₃

Molecular Luj: 994 86

Melting Point: N / A

Boiling Point: 982.73 degree C ntawm 760 mmHg (Tshaj tawm)

Flash Point: 85 degree

Qhov ceev: 1.49 g / cm3³(Xav tau)

Cov tsos: Crystalline khoom

Solubility: Soluble hauv DMSO (10 mg / ml)

Acidity coefficient: 2.66 ± 0.50 (Predicted)

Refractive Index: 1.61 (Tshaj tawm)

Fluorescent: λex 496 nm, λem 516 nm hauv 0.1 M Tris pH 8.0

Cia txias: Desiccate ntawm -20 degree C

Daim ntawv thov: Calcein-AM(CAS: 148504-34-1)yog hydrophobic non-fluorescent sojntsuam uas tuaj yeem nkag mus rau hauv cov ntshav plasma thiab tuaj yeem hydrolyzed rau calcein (sc-202090). Calcein-AM yog ib qho fluorescent tsis tshua muaj nqi thiab tsis zoo molecule. Kev sojntsuam Calcein-AM tuaj yeem siv los ua cov cell nyob thiab tau pom tias muaj fluoresce ci ntsuab hauv cytoplasmic Schwann hlwb. Calcein-AM tau raug tshaj tawm tias yog ib qho nruab nrab substrate rau Mdr (P-glycoprotein (Pgp) thiab multidrug resistance protein (MRP)) thiab tau siv hauv cov kev tshawb fawb cytometry los txheeb xyuas cov haujlwm ntawm P-gp thiab MRP. Cov kev tshawb fawb qhia tias Calcein-AM tuaj yeem siv los kuaj MDR kev sib haum xeeb thiab raug thauj los ntawm PGP los ntawm cov plasma membrane. Mitochondrial permeability kev tshawb fawb tau siv Calcein-AM ua cytosolic fluorophore. Calcein-AM tau siv los ua cytosolic fluorophore hauv mitochondrial permeability kev tshawb fawb rau cov duab pore hloov.

Siv:

1. Feller, N., et al. 1995. Nr. J. Cancer. 72: 3 :ua. PIB: 76695599

2. Feller, N., et al. 1995. FEB Lett. 368: 3 ib. PIB: 7628644

3. Essodaigui, M., et al. 1998. Biochemistry. 37: {3}}. PIB: 9485370

4. Lemasters, JJ, et al. Xyoo 1998. Biochim. Biophys. Acta. 1366: 3 : kuv. PIB: 9714796

5. Dhar, S., et al. Xyoo 1998.Eur. J. Pharmacol. 346: 3 : kuv. PIB: 9652375

Ntim & Xa

Pob: 5g / 10g / 25g / 50g / bulk pob

Kev Thauj Mus Los: los ntawm FeDex lossis los ntawm hiav txwv shipping lossis cov neeg siv khoom xav tau

Kev Qhia Txog Tus Me Nyuam: Hauv 3-5 hnub tom qab them tag nrho.

Cov nqe lus them nqi yooj yim: txhawb T / T, Paypal, Credit Card.

Cim npe nrov: cas:148504-34-1|calcein-am, nqe, hais, luv nqi, hauv Tshuag, muag