CAS 877399-52-5|Crizotinib
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CAS 877399-52-5|Crizotinib

CAS 877399-52-5|Crizotinib

Cov mis mos molecular: C21H22Cl2FN5O
Molecular Luj: 450.34
EINECS: 638-814-9
Purity: 97% Min.
Pob: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
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Crizotinib es un inhibidor de la tirosina quinasa (TKI) de molécula pequeña que se dirige a la quinasa del linfoma anaplásico (ALK), ROS1, ya otro receptor de tirosina quinasa oncogén, MET.

Specification ntawm CAS 877399-52-5|Crizotinib

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SPECIFICATION

Melting point

192 degree

Cia temp.

Chav ntsuas kub

Xim

Dawb rau tan

Daim ntawv

hmoov

Qhov ntom

1.47 g / cm3

Boiling point

5 99.2 o ua

pka ua

9.81

CAS DataBase Reference

877399-52-5

Synthesis ntawmCAS 877399-52-5|Crizotinib

image

Cov xwm txheej

Nrog hydrogenchloride Hauv 1, 4-dioxane; dichloromethane; dej ntawm 0 - 20 degree; rau 4h;. Inert cua;

Kev siv

Cui, J. Jean; Tran-Dubé, Michelle; Shen, Hong; Nambu, Mitchell; Kung, Pei-Pei; Pairish, Mason; Jia, Li; (…) Kania, Robert S.; Edwards, Martin P.

[Journal of Medicinal Chemistry, 2011, vol. 54, nr 18, p. 6342 - 6363]

Cim npe nrov: cas 877399-52-5|crizotinib, nqe, hais, luv nqi, hauv Tshuag, kev muag khoom

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