CAS 545445-44-1|3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2 (1H) - ib
Cov mis mos molecular: C20H25N3O3
Molecular Luj: 355.43
EINECS: 1308068-626-2
Purity: 97% Min.
Pob: 1 g / 5 g / 25 g / 100 g / 1 kg
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Khoom Taw qhia
Taw qhia
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2 (1H)-ib qho yog qhov nruab nrab rau kev npaj ntawm apixaban.
Specification ntawm CAS 545445-44-1|3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2 (1H) - ib
Yam khoom | SPECIFICATION |
Boiling point | 625 0 degree |
pka ua | 3.25 |
cia temp. | Muab kaw rau hauv qhuav, 2-8 degree |
ceev | 1.267 |
Synthesis ntawmCAS 545445-44-1|3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2 (1H) - ib
Cov xwm txheej
Theem #1: 5-Chlorovaleroyl chloride; 1-(4-aminophenyl)-3-(morpholin-4-yl)-5,6-dihydropyridin-2(1H)-ib nrog tetrabutylamomium bromide; sodium hydroxide Hauv dichloromethane; dej ntawm 0 - 5 degree ; rau 1h;.
Theem #2: Nrog potassium hydroxide Hauv dichloromethane; dej ntawm 20 degree; Reagent / catalyst; Solvent; Kub;
Cim npe nrov: cas 545445-44-1,545445-44-1,3-morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl){{7} }, 6-dihydropyridin-2(1h)-ib, nqe, hais, luv nqi, hauv Tshuag, muag
